Recent advances in multiplexing single-cell transcriptomics across experiments are enabling the high-throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally …
Learning robust representations can help uncover underlying biological variation in scRNA-seq data. Disentangled representation learning is one approach to obtain such informative as well as interpretable representations. Here, we learn disentangled …
Large single-cell atlases are now routinely generated with the aim of serving as reference to analyse future smaller-scale studies. Yet, learning from reference data is complicated by batch effects between datasets, limited availability of …
While generative models have shown great success in sampling high-dimensional samples conditional on low-dimensional descriptors (stroke thickness in MNIST,hair color in CelebA, speaker identity in WaveNet), their generation out-of-sample poses …
Accurately modeling cellular response to perturbations is a central goal of computational biology. While such modeling has been based on statistical, mechanistic and machine learning models in specific settings, no generalization of predictions to …
Network traffic classification has become more important with the rapid growth of Internet and online applications. Numerous studies have been done on this topic which have led to many different approaches. Most of these approaches use predefined …